Profhilo Treatment

Profhilo Treatment

What is Profhilo®?

Profhilo® is a patented technology of bio-remodelling injectable. It is the first “injectable skincare” that addresses skin laxity and signs of aging through the bio-stimulation of collagen, elastin and adipocytes (fats) stem cells that are lost through skin aging.

Profhilo® is also the only HA injectable that is able to improve skin laxity through the stimulation of elastin. With one of the highest concentrations of HA on the market (64mg / 2ml) it intensely boosts skin hydration levels.

This is made possible with NAHYCO® Technology where 32mg of high molecular HA (H-HA) and 32mg of low molecular HA (L-HA), bind together through thermal cross-linking to form the only Hybrid Cooperative Complex Hyaluronic (HCC) Acid. In addition to its skin hydrating properties, HCC Acid also stimulates collagen and elastin to remodel sagging tissue for firmer, younger looking skin.

Profhilo® vs. Fillers vs. Skinboosters

Skinboosters uses the principle of replacing lost hyaluronic acid in our skin to restore hydration and elasticity while Fillers are designed to replace lost volume or fill up folds.

Profhilo® is not a dermal filler, nor is it a skin booster. While it is also a Hyaluronic Acid based product, it is designed to remodel multi-layer skin tissue. It works in the epidermis, dermis and superficial fat compartments to target and treat the source of aging and not just the aging symptoms. This is done in 3 ways:

Effects of Profhilo®

In 1-3 days:

Once injected, Profhilo® replenishes the hyaluronic acid in the skin. Patient’s skin hydration level will be improved and fine lines will be plumped up.

Gradually in a few weeks:

Clinical studies shown significant improvements in skin elasticity, hydration, wrinkles, skin texture and skin tightening*. Most patients often experience firmer, bouncier and more youthful looking skin. Profhilo® also helps with tissue repair and improves the appearances of scars.

Full Profhilo® Treatment results:

The full effects of Profhilo® take up to 12 weeks after the first treatment, as the bio-remodelling process takes time to complete. Another dose of Profhilo® is recommended 4 weeks after the first treatment for optimal results.

Where can Profhilo® be injected?

Profhilo® is most commonly used on the cheek area and lower face, but can also be used to improve the appearance of skin on the following areas:

  • Forehead and Eye area
  • Neck and Décolletage
  • Arms, Hands
  • Knees
  • Chest and Abdomen
  • Depressed acne scars

Administering Profhilo®:

Profhilo® uses the unique Bio Aesthetic Points (BAP) technique, with just 5 injections per side.

The Hyaluronic Acid diffuses across the widest sections of the face through subdermal patterns, stimulating the production of elastin, collagen and hydration in the skin. With minimal injection points, this increases patient’s compliance, reduction in pain and lowers the possibility of bruising or hematoma. Ideally, the first 2 to 3 sessions of Profhilo® should be administered 1 month apart, for maintenance and optimal results, each session should be repeated every 6-9 months.

Can Profhilo® be used with other treatments?

Yes! Profhilo® delivers great results as a treatment on its own or in combination with other aesthetics treatments.

For lifting:

Profhilo® can be safely combined with energy-based devices such as Ulthera and Thermage for more permanent skin tightening that lasts up to a year, or Exilis Elite for instant lift.

For loss of volume:

Profhilo® can be combined with fillers to plump up sunken areas for a more youthful look. The two treatments work in synergy to improve the appearance – fillers will replace lost volume, while Profhilo® finishes the job by stimulating collagen and elastin and restoring hydration.

For improvement in scars and discolouration:

Profhilo® also works well with Laser Peels and Pico Laser for the improvements of scars and skin discolouration.


Efficacy and tolerance of an injectable medical device containing stable hybrid cooperative complexes of high- and low-molecular-weight hyaluronic acid: a monocentric 16 weeks open-label evaluation by Adele Sparavigna and Beatrice Tenconi. Clin Cosmet Investig Dermatol. 2016; 9: 297–305.

Important note:
The Ministry of Health of Singapore does not allow the publishing of before and after photographs and patient testimonials in advertising materials. If you visit our clinics for more information, we will be happy to show you more photographs and pictures of our patients.


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